If new to both plugins, I would recommend starting with Cineware and Cinema 4D Lite, since they come free with After Effects. Once you have experimented with it, you can better gauge if it is adequate for your needs, and from there decide whether to move to Element 3D or fully commit to the full version of Cinema 4D.
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Element 3d Plugin After Effects Free 19
A fraction of DNAJC5 is also localized to a perinuclear membrane compartment, which is largely free of LAMP1 and not stained well by a LysoTracker dye. However, this compartment can be weakly labeled by LysoTracker after prolonged staining (movie S2), suggesting that it might be a pre-lysosomal compartment. The localization of DNAJC5 to this compartment does not require its J-domain but depends on palmitoylation of DNAJC5 since both the ANCL-associated disease mutants (this study) and a CS-domain deleted mutant fail to associate with this compartment [19]. Additionally, we identified a DNAJC5 binding partner named SLC3A2, which regulates the peri-nuclear localization of DNAJC5. SLC3A2 is a type II membrane glycoprotein capable of interacting with six light chain molecules, forming a set of amino acid transporters on the plasma membrane [52]. Moreover, additional adaptors such as LAPTM4B can retain a SLC3A2-containing transporter in endolysosomes, regulating the amino acid balance between endolysosome and cytoplasm and thus the MTOR signaling [57]. Whether SLC3A2-dependent regulation of the DNAJC5 localization requires additional components awaits further characterization. 2ff7e9595c
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